ViennaLab Diagnostics GmbH

Confirm thalassemia diagnosis with region-tailored assays, and identify β-thalassemia modifiers.

Thalassemias are characterized by inherited defective hemoglobin synthesis leading to microcytic, hemolytic anemias. The clinical heterogeneity ranges from asymptomatic to very severe forms requiring regular blood transfusions. Globin StripAssays® detect common thalassemia-causing genetic variants worldwide, and the β-Thal Modifier StripAssay® identifies co-inherited variants known to ameliorate severity of beta-thalassemia.

 

Thalassemia

 

  • Severe thalassemia is life-limiting and poses a major public health burden in Mediterranean countries, Africa, the Middle East, South-East Asia, and the Indian subcontinent.
  • Mutations in the alpha- and beta-globin genes lead to reduced or abolished globin-chain synthesis or cause structurally abnormal hemoglobin.
  • Genetic analysis is required to confirm the clinical diagnosis and is indispensable for genetic counseling.
  • Apart from bone marrow transplantation, no ultimate cure is available up-to-date. However, identifying favourable genetic modifiers in patients help to predict the severity of beta-thalassemia phenotypes.

 

ProductReg. Stat.REFUnit SizeIFUBrochure
α-Globin StripAssay® IVDR CE01234-16010 tests

PDF

β-Globin StripAssay® MED CE/IVD4-13020 tests

PDF

PDF

β-Globin StripAssay® IME CE/IVD4-14020 tests

PDF

PDF

β-Globin StripAssay® SEA CE/IVD4-15020 tests

PDF

PDF

β-Thal Modifier StripAssay® CE/IVD4-17020 tests

PDF

PDF

We use Matomo to analyze the access to our website. We pass on information about your use of our website to our partners for analysis. Our partners may combine this information with other data that you have provided to them or that they have collected as part of your use of the services. I agree.

Deny Allow