Cardiovascular Diseases (CVD) are often caused by a combination of a genetic predisposition and an unhealthy lifestyle. CVD StripAssays® and RealFast™ Assays identify various combinations of genetic CVD risk factors.
Cardiovascular Diseases (CVD)
- The two major manifestations of CVD are atherosclerosis and venous thrombosis.
- The risk for atherosclerosis is increased by the combination of an unhealthy lifestyle and variants of genes involved in endothelial dysfunction, hyperlipidemia, hypertension, and inflammation.
- Correspondingly, the interplay of adverse influences (female hormone intake, lack of physical activity, surgery, cancer) and certain genetic variants enhance the susceptibility to develop thrombosis.
- Testing for disease-associated genetic variants in conjunction with an adaptation of life style can greatly contribute to decrease an individual's CVD risk.
pdf Product note 01: CVD Marker
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Citations:
1. Younis, M., et al., 2023. Maternal Thrombophilic and Hypofibrinolytic Genetic Variants in Idiopathic Recurrent Pregnancy Loss: a Continuing Mystery. Reproductive Sciences 30, 656–666. doi: 10.1007/s43032-022-01063-1.
2.Lenicek Krleza J., et al., 2022. Inherited Thrombophilia Associated With Ischemic Pediatric Stroke in Parent-Child Pairs. Pediatric Neurology, vol. 146. doi: 10.1016/j.pediatrneurol.2023.06.017.
3. Lapić I., et al., 2022. Association of polymorphisms in genes encoding prothrombotic and cardiovascular risk factors with disease severity in COVID-19 patients: A pilot study. Journal of medical virology vol. 94,8: 3669-3675. doi: 10.1002/jmv.27774.
4. Krohn, J., et al., 2022. Optimisation of individual cardiovascular risk assessment in a German coronary artery disease cohort using a commercial test for genetic polymorphisms – a pilot study. Acta Cardiologica, 78(1), 124–134. doi: 10.1080/00015385.2022.2116810.
5. Mohammed W., et al., 2018. Molecular assessment of some cardiovascular genetic risk factors among Iraqi patients with ischemic heart diseases. International journal of health sciences vol. 12,3: 44-50. PMCID: PMC5969780.