Characterize HLA-B*27 subtypes associated with seronegative spondyloarthropathies such as Morbus Bechterew.

HLA-B*27 is a genetic risk factor for seronegative spondyloarthropathies, such as ankylosing spondylitis, reactive arthritis, juvenile rheumatoid arthritis and anterior uveitis. ViennaLab HLA-B27 assays detect the majority of currently known HLA-B*27 variants except some rare alleles.

 

HLA-B27

 

  • Ankylosing spondylitis (AS), also known as Bechterew´s disease is the most prevalent spondyloarthropathy. Symptoms at the onset of the disease are usually nonspecific, posing difficulties for a firm diagnosis.
  • HLA-B molecules play an important role in immunity. Studies showed a high correlation of HLA-B*27 alleles and AS patients. Differentiating between HLA-B*27 positive and negative patients is therefore an important parameter for diagnosing spondyloarthropathies.
  • Early and adequate treatment ameliorates the course of the disease.

  pdf Productnote 02: HLA-B27

 

ProductREFUnit SizeIFUBrochure
HLA-B27 RealFast™ Assay7-620
7-623
100 rxn
32 rxn

PDF

HLA-B27 StripAssay®4-32020 tests

PDF

PDF